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For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

Flashcards

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Card 1 of 210
DiseaseCardiovascular

Acute Coronary Syndrome (STEMI)

Recall: Pathophysiology · S/Sx · Gold Standard Dx · First-line Tx · Pearl

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DiseaseCardiovascular

Acute Coronary Syndrome (STEMI)

Pathophysiology
Plaque rupture → thrombus → complete coronary occlusion → transmural ischemia/infarction.
S/Sx
Crushing substernal chest pain >20 min, radiates to L arm/jaw, diaphoresis, dyspnea, N/V.
Gold Standard Dx
ECG (ST elevation ≥1mm in ≥2 contiguous leads) + troponin. Coronary angiography is definitive.
First-line Tx
MONA-B + reperfusion: ASA + P2Y12, anticoagulation, statin; PCI <90 min (or fibrinolytics if PCI unavailable).

Time is muscle — door-to-balloon <90 min. Do NOT give nitrates if RV infarct or recent PDE-5 inhibitor.