Renal
~5% of blueprintAKI/CKD, electrolytes, nephrolithiasis, acid-base, glomerular disease.
Disease Profiles
Anatomy
- Region
- Retroperitoneal, ~T12–L3 (the right kidney sits lower due to the liver).
- Key Structures
- Cortex, medullary pyramids, renal pelvis, hilum (artery, vein, ureter); the ureters narrow at three points.
- Clinical Correlation
- Stones lodge at the three narrowings; flank/CVA tenderness suggests pyelonephritis.
High-Yield Pearl
Kidney stones lodge at the 3 ureteral narrowings: UPJ, pelvic brim, and ureterovesical junction.
- Region
- Functional unit spanning the renal cortex & medulla.
- Key Structures
- Glomerulus/Bowman capsule, proximal tubule, loop of Henle, distal tubule, collecting duct.
- Clinical Correlation
- Diuretics target specific segments; the proximal tubule is the site of Fanconi syndrome.
High-Yield Pearl
Diuretic sites: acetazolamide (PCT), loop diuretics (thick ascending limb), thiazides (DCT), K-sparing (collecting duct).
First-line drugs
All pharmacologyLearn it in your courses
Gross Anatomy
Physiology