Ibuprofen
NSAID- Drug Class
- NSAID
- Mechanism of Action (MOA)
- Reversibly inhibits COX-1 and COX-2 → ↓ prostaglandin synthesis.
- Black Box Warning
- Increased risk of serious cardiovascular thrombotic events and of GI bleeding/perforation.
- Clinical Notes
- Pain, fever, inflammation. GI ulcers, renal impairment (afferent vasoconstriction), fluid retention; avoid in CKD/HF and 3rd-trimester pregnancy.
- Source
- FDA label
Sources
Reviewed September 2026- FDA label — FDA / DailyMed
Checked against the guideline or standard reference the exam keys to. If it has moved, use Report an error below.
Used for
Same family
Got a pharmacology lecture that covers Ibuprofen? Turn it into flashcards and board-style questions, free. Drop it on the home page
All pharmacology