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For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

HomePharmacologyAcetaminophen

Acetaminophen

Analgesic / Antipyretic
Drug Class
Analgesic / Antipyretic
Mechanism of Action (MOA)
Centrally acting; weak central COX inhibition (mechanism incompletely understood) with minimal peripheral anti-inflammatory effect.
Clinical Notes
First-line analgesic/antipyretic; safe in pregnancy and PUD. Hepatotoxic in overdose (max ~4 g/day) — antidote N-acetylcysteine.
Source
FDA label (DailyMed)
All pharmacology