Acetaminophen

Analgesic / Antipyretic
Drug Class
Analgesic / Antipyretic
Mechanism of Action (MOA)
Centrally acting; weak central COX inhibition (mechanism incompletely understood) with minimal peripheral anti-inflammatory effect.
Clinical Notes
First-line analgesic/antipyretic; preferred analgesic in pregnancy; safe in PUD. Hepatotoxic in overdose (max 4 g/day from all sources) — antidote N-acetylcysteine.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

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Used for

Same family

Pain relievers · 6 drugs

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