Body Systems
14 organ systems (94%) + Professional Practice (6%)The NCCPA PANCE Blueprint, organized by organ system and ordered by exam weight. Each system collects its High-Yield disease profiles, anatomy, and pharmacology. Drug cards live in Pharmacology, grouped by family.
View the official NCCPA PANCE Blueprint- Cardiovascular11%
Highest-yield system. ACS, HF, arrhythmias, valvular disease.
- Pulmonary9%
Obstructive vs. restrictive, PE, pneumonia, pleural disease.
- Gastrointestinal/
Nutrition8% Luminal GI, hepatobiliary, pancreatic, nutritional deficiencies.
- Musculoskeletal8%
Fractures, arthropathies, sports injuries, low back pain.
- Neurology7%
Stroke, seizures, headache, neurodegenerative disease.
- Infectious Disease7%
Bacterial, viral, fungal, parasitic; antimicrobial selection.
- Psychiatry/
Behavioral7% Mood, anxiety, psychotic, substance use disorders.
- Reproductive7%
Obstetrics, gynecology, male & female reproductive.
- Endocrine6%
Thyroid, diabetes, adrenal, pituitary, calcium disorders.
- Eyes/
Ears/ Nose/ Throat6% Red eye, otitis, sinusitis, pharyngitis, vertigo.
- Hematology5%
Anemias, coagulopathies, hematologic malignancies.
- Renal5%
AKI/CKD, electrolytes, nephrolithiasis, acid-base, glomerular disease.
- Genitourinary4%
UTI, bladder & urethral disorders, incontinence, male GU.
- Dermatology4%
Eczematous, papulosquamous, infectious, neoplastic lesions.
- Professional Practice6%
Cross-cutting: PA role & scope of practice, ethics, mandated reporting, risk management, and evidence-based medicine.