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PANCE Body Systems
  • Cardiovascular
    11%
  • Pulmonary
    9%
  • Gastrointestinal/Nutrition
    8%
  • Musculoskeletal
    8%
  • Neurology
    7%
  • Infectious Disease
    7%
  • Psychiatry/Behavioral
    7%
  • Reproductive
    7%
  • Endocrine
    6%
  • Eyes/Ears/Nose/Throat
    6%
  • Hematology
    5%
  • Renal
    5%
  • Genitourinary
    4%
  • Dermatology
    4%
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About·Tools·Terminology·Privacy Policy·Terms of Service·PANCE Blueprint

PANCE® is a registered trademark of the National Commission on Certification of Physician Assistants (NCCPA). This application is an independent study resource and is not affiliated with, sponsored by, or endorsed by the NCCPA.

For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

Cardiovascular

~11% of blueprint

Highest-yield system. ACS, HF, arrhythmias, valvular disease.

FlashcardsPrep Rounds
Audio Overview· Cardiovascular
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AI-generated conversational overview — a high-yield primer for passive review. Verify specifics against the cards below.

Disease Profiles

Anatomy

Region
Within the myocardium, from the right atrium to the ventricles.
Key Structures
SA node (RA) → AV node → Bundle of His → R/L bundle branches → Purkinje fibers.
Clinical Correlation
SA node = dominant pacemaker; AV nodal delay = PR interval; block at His/branches → bundle branch & heart block.
High-Yield Pearl

SA node is the pacemaker; the AV node is the gatekeeper that delays conduction so the atria empty first.

Region
Epicardial surface of the heart, arising from the aortic root.
Key Structures
LAD & LCx (from left main), RCA; RCA → PDA in ~85% (right-dominant).
Clinical Correlation
LAD occlusion → anterior MI (V1–V4); RCA → inferior MI (II, III, aVF); LCx → lateral MI (I, aVL, V5–V6).
High-Yield Pearl

RCA supplies the SA node in ~60% — inferior MI → watch for bradyarrhythmias & AV block.

Region
Anchored to the fibrous cardiac skeleton at the AV and outflow junctions.
Key Structures
AV valves: tricuspid (R), mitral/bicuspid (L). Semilunar: pulmonic (R), aortic (L).
Clinical Correlation
Auscultation: Aortic (R 2nd ICS), Pulmonic (L 2nd ICS), Tricuspid (L lower sternal), Mitral (apex).
High-Yield Pearl

“APT M” — All Physicians Take Money — Aortic → Pulmonic → Tricuspid → Mitral auscultation sites.

Region
Fibroserous sac enclosing the heart and great-vessel roots.
Key Structures
Fibrous pericardium + serous (parietal & visceral/epicardium) layers; pericardial space (~15–50 mL fluid).
Clinical Correlation
Inflammation → pericarditis (friction rub, diffuse ST elevation); fluid → effusion → tamponade.
High-Yield Pearl

Beck’s triad = hypotension + JVD + muffled heart sounds → cardiac tamponade (a clinical emergency).