Carvedilol

Nonselective β-/α₁-Blocker
Drug Class
Nonselective β-/α₁-Blocker
Mechanism of Action (MOA)
Blocks β1, β2, and α1 receptors → ↓ heart rate/contractility plus vasodilation.
Clinical Notes
One of three β-blockers with HFrEF mortality benefit (with metoprolol succinate, bisoprolol). Take with food to slow absorption and reduce orthostasis.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

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Used for

Same family

Beta-blockers · 4 drugs

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