• PA
    PA School SurvivalDidactic Year
Subjects
  • 📖Medical Terminology
  • 🦴Gross Anatomy
    • Study Playbook
    • By Region
    • PNS Chart
    • My Lectures
    • Practice
  • 🧬Immunology & Genetics
    • Study Playbook
    • By Topic
    • My Lectures
    • Practice
  • 🧪Physiology
    • Study Playbook
    • By System
    • My Lectures
    • Practice
My material
  • 🗂️My Library
  • ✍️Notes & Sketches
Study Tools
  • 🎓Flashcards
  • 📡To revisit
  • 🗓️Calendar
  • 📈Progress
  • ✅Prep Rounds
  • 🧬Body Systems
  • 💊Pharmacology
  • 🔗Offsite Resources
  • 🧭Guide & FAQ
  • 💡
    Suggest a FeatureLet us know what we can do better — we genuinely want to help you in class.
PANCE Body Systems
  • 🫀Cardiovascular
    11%
  • 🫁Pulmonary
    9%
  • 🍎Gastrointestinal/Nutrition
    8%
  • 💪Musculoskeletal
    8%
  • 🧠Neurology
    7%
  • 🦠Infectious Disease
    7%
  • 💭Psychiatry/Behavioral
    7%
  • 🤰Reproductive
    7%
  • 🦋Endocrine
    6%
  • 👁️Eyes/Ears/Nose/Throat
    6%
  • 🩸Hematology
    5%
  • 🫘Renal
    5%
  • 💧Genitourinary
    4%
  • 🖐️Dermatology
    4%
Weights are study aids — verify each exam cycle.
⌘K
NotesPricingSign in
About·Tools·Terminology·Anatomy playbook·Anatomy by region·Immunology & genetics·Immunology playbook·Physiology·Physiology playbook·Privacy Policy·Terms of Service·PANCE Blueprint

PANCE® is a registered trademark of the National Commission on Certification of Physician Assistants (NCCPA). This application is an independent study resource and is not affiliated with, sponsored by, or endorsed by the NCCPA.

For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

HomePharmacologyLabetalol

Labetalol

Combined Alpha-/Beta-Blocker
Drug Class
Combined Alpha-/Beta-Blocker
Mechanism of Action (MOA)
Blocks β1, β2, and α1 receptors → ↓ heart rate/contractility plus vasodilation (↓ afterload).
Clinical Notes
Hypertensive emergencies and hypertension in pregnancy/preeclampsia (a first-line agent). IV for acute control; do not stop abruptly; contraindicated in bronchial asthma (β2 blockade).
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

Checked against the guideline or standard reference the exam keys to. If it has moved, use Report an error below.

All pharmacology