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HomePharmacologyLabetalol

Labetalol

Combined Alpha-/Beta-Blocker
Drug Class
Combined Alpha-/Beta-Blocker
Mechanism of Action (MOA)
Blocks β1, β2, and α1 receptors → ↓ heart rate/contractility plus vasodilation (↓ afterload).
Clinical Notes
Hypertensive emergencies and hypertension in pregnancy/preeclampsia (a first-line agent). IV for acute control; do not stop abruptly; caution in asthma (β2 blockade).
Source
FDA label (DailyMed)
All pharmacology