• PA
    PA School SurvivalDidactic Year
Subjects
  • 📖Medical Terminology
  • 🦴Gross Anatomy
    • Study Playbook
    • By Region
    • PNS Chart
    • My Lectures
    • Practice
  • 🧬Immunology & Genetics
    • Study Playbook
    • By Topic
    • My Lectures
    • Practice
  • 🧪Physiology
    • Study Playbook
    • By System
    • My Lectures
    • Practice
My material
  • 🗂️My Library
  • ✍️Notes & Sketches
Study Tools
  • 🎓Flashcards
  • 📡To revisit
  • 🗓️Calendar
  • 📈Progress
  • ✅Prep Rounds
  • 🧬Body Systems
  • 💊Pharmacology
  • 🔗Offsite Resources
  • 🧭Guide & FAQ
  • 💡
    Suggest a FeatureLet us know what we can do better — we genuinely want to help you in class.
PANCE Body Systems
  • 🫀Cardiovascular
    11%
  • 🫁Pulmonary
    9%
  • 🍎Gastrointestinal/Nutrition
    8%
  • 💪Musculoskeletal
    8%
  • 🧠Neurology
    7%
  • 🦠Infectious Disease
    7%
  • 💭Psychiatry/Behavioral
    7%
  • 🤰Reproductive
    7%
  • 🦋Endocrine
    6%
  • 👁️Eyes/Ears/Nose/Throat
    6%
  • 🩸Hematology
    5%
  • 🫘Renal
    5%
  • 💧Genitourinary
    4%
  • 🖐️Dermatology
    4%
Weights are study aids — verify each exam cycle.
⌘K
NotesPricingSign in
About·Tools·Terminology·Anatomy playbook·Anatomy by region·Immunology & genetics·Immunology playbook·Physiology·Physiology playbook·Privacy Policy·Terms of Service·PANCE Blueprint

PANCE® is a registered trademark of the National Commission on Certification of Physician Assistants (NCCPA). This application is an independent study resource and is not affiliated with, sponsored by, or endorsed by the NCCPA.

For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

HomeCardiovascularAortic Dissection
🫀

Aortic Dissection

Cardiovascular · ~11% of blueprint
🔬Pathophysiology
Intimal tear → blood tracks into the media → false lumen propagation. Risk: HTN, Marfan/connective-tissue disease, bicuspid valve, cocaine.
🩺Signs & Symptoms
Sudden tearing/ripping chest pain radiating to the back; inter-arm BP differential; may cause AR murmur, tamponade, stroke, or limb ischemia.
🎯Gold Standard Diagnosis
CT angiography (stable patient); TEE if unstable. Widened mediastinum on CXR is a clue.
💊First-line Treatment
Stanford A (ascending) → emergent surgery. Stanford B (descending) → medical: IV beta-blocker (esmolol) to lower HR/BP FIRST, then a vasodilator.
Drug cardsLabetalolMetoprololHydralazine
High-Yield Pearl

Beta-blocker BEFORE vasodilator (avoid reflex tachycardia → ↑ shear stress). Type A = surgery, Type B = medical unless complicated.

Sources

Reviewed September 2026
  1. 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease — ACC/AHA, 2022
  2. StatPearls: Aortic Dissection — NCBI Bookshelf / StatPearls, 2025

Checked against the guideline or standard reference the exam keys to. If it has moved, use Report an error below.

More Cardiovascular conditions

  • Acute Coronary Syndrome (STEMI)
  • Acute Pericarditis
  • Aortic Stenosis
  • Atrial Fibrillation
  • Deep Vein Thrombosis
  • Heart Failure (HFrEF)
  • Hyperlipidemia
  • Hypertension (Essential)
  • Hypertrophic Cardiomyopathy
  • Infective Endocarditis
  • Mitral Regurgitation
  • Peripheral Arterial Disease
All Cardiovascular