Metoprolol

Beta-1 Selective Blocker

Drug Class: Beta-1 Selective Blocker
Mechanism of Action (MOA): Selective β1 antagonist → ↓ heart rate, ↓ contractility, ↓ AV conduction & myocardial O₂ demand.
Black Box Warning: Ischemic heart disease — do NOT stop abruptly: abrupt cessation can cause severe exacerbation of angina, MI, and ventricular arrhythmias. Taper over 1–2 weeks.
Clinical Notes: Succinate (ER) is the HF-approved salt; β1-selective.
Source: FDA label (DailyMed)