Hydralazine

Direct Arterial Vasodilator
Drug Class
Direct Arterial Vasodilator
Mechanism of Action (MOA)
Direct arteriolar smooth-muscle relaxation → ↓ afterload.
Clinical Notes
With isosorbide dinitrate for HFrEF in Black/ACE-intolerant patients; IV for hypertensive emergency in pregnancy. Reflex tachycardia; drug-induced lupus.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

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Used for

Same family

Nitrates & direct vasodilators · 2 drugs

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