- 🔬Pathophysiology
- Placental ischemia/hypoperfusion -> maternal endothelial dysfunction -> hypertension & proteinuria after 20 weeks.
- 🩺Signs & Symptoms
- New HTN ≥140/90 with proteinuria after 20 weeks; headache, visual changes, RUQ pain, edema if severe.
- 🎯Gold Standard Diagnosis
- BP ≥140/90 on two occasions + proteinuria (or end-organ dysfunction) after 20 weeks gestation.
- 💊First-line Treatment
- Definitive treatment is delivery; magnesium sulfate for seizure prophylaxis; labetalol/hydralazine for BP.