Preeclampsia

Reproductive · ~7% of blueprint

Pathophysiology: Placental dysfunction → endothelial damage and vasospasm → hypertension & proteinuria after 20 weeks.
Signs & Symptoms: New HTN ≥140/90 with proteinuria after 20 weeks; headache, visual changes, RUQ pain, edema if severe.
Gold Standard Diagnosis: BP ≥140/90 on two occasions + proteinuria (or end-organ dysfunction) after 20 weeks gestation.
First-line Treatment: Definitive treatment is delivery; magnesium sulfate for seizure prophylaxis; labetalol/hydralazine for BP.

High-Yield Pearl

Magnesium sulfate prevents eclamptic seizures; delivery is the only cure.

More Reproductive conditions