Magnesium Sulfate

Electrolyte / Anticonvulsant
Drug Class
Electrolyte / Anticonvulsant
Mechanism of Action (MOA)
Anticonvulsant with a CNS depressant effect; peripheral vasodilation. Exact mechanism not established (likely Ca²⁺/NMDA antagonism).
Clinical Notes
Labeled to prevent and control seizures in preeclampsia and eclampsia. Toxicity: deep tendon reflexes diminish then disappear -> respiratory paralysis; heart block may occur — keep an injectable calcium salt available.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

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Used for

Same family

Reproductive & urinary drugs · 6 drugs

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