Oxytocin

Uterotonic (Posterior Pituitary Hormone)
Drug Class
Uterotonic (Posterior Pituitary Hormone)
Mechanism of Action (MOA)
Activates uterine oxytocin receptors → rhythmic myometrial contraction; also drives milk letdown.
Black Box Warning
Not indicated for elective induction of labor (benefit-risk data inadequate).
Clinical Notes
Labor induction/augmentation and first-line for postpartum hemorrhage. Watch uterine tachysystole/rupture and fetal distress; hyponatremia (ADH-like effect) with prolonged high-dose infusion.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

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