Tamsulosin

Drug Class

Alpha-1 Adrenergic Antagonist

Mechanism of Action (MOA)

Selective α1A blockade relaxes prostatic and bladder-neck smooth muscle → improved urinary flow.

Clinical Notes

First-line for symptomatic BPH and, off-label, medical expulsive therapy for distal ureteral stones. Orthostatic hypotension/first-dose syncope; intraoperative floppy iris syndrome (warn before cataract or glaucoma surgery); retrograde ejaculation.

Source

FDA label

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