Pelvic Inflammatory Disease

Reproductive · ~7% of blueprint
Pathophysiology
Ascending infection (often N. gonorrhoeae, C. trachomatis) → endometritis and salpingitis.
Signs & Symptoms
Lower abdominal/pelvic pain, cervical motion tenderness, discharge, fever, dyspareunia.
Gold Standard Diagnosis
Clinical (cervical motion / adnexal / uterine tenderness) + NAAT; laparoscopy if diagnosis unclear.
First-line Treatment
Ceftriaxone IM + doxycycline + metronidazole x 14 days; treat sex partners.
High-Yield Pearl

Cervical motion tenderness ('chandelier sign'), uterine or adnexal tenderness supports presumptive PID; untreated → infertility & ectopic risk.

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Sources

Reviewed September 2026
  1. Sexually Transmitted Infections Treatment Guidelines, 2021 - Pelvic Inflammatory Disease (PID) — CDC, 2021
  2. StatPearls: Pelvic Inflammatory Disease — StatPearls Publishing / NCBI Bookshelf, 2026

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