Ceftriaxone

Cephalosporin (3rd-Generation)
Drug Class
Cephalosporin (3rd-Generation)
Mechanism of Action (MOA)
β-lactam: inhibits PBPs → impairs cell-wall synthesis; broad gram-negative coverage and crosses the BBB.
Clinical Notes
Workhorse for meningitis, pyelonephritis, and gonorrhea; avoid co-administration with calcium in neonates.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

Checked against the guideline or standard reference the exam keys to. If it has moved, use Report an error below.

Used for

Same family

Cephalosporins & carbapenems · 4 drugs

Got a pharmacology lecture that covers Ceftriaxone? Turn it into flashcards and board-style questions, free. Drop it on the home page

All pharmacology