Metronidazole

Nitroimidazole

Drug Class: Nitroimidazole
Mechanism of Action (MOA): Forms toxic free radicals that damage microbial DNA (anaerobes & protozoa).
Black Box Warning: Carcinogenicity: shown to be carcinogenic in animal models (mice/rats); avoid unnecessary use — reserve for approved indications.
Clinical Notes: Anaerobes, C. difficile, Giardia, BV, trichomoniasis; disulfiram-like reaction with alcohol.
Source: FDA label (DailyMed)