PA School SurvivalDidactic Year

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PANCE Body Systems

Cardiovascular
11%
Pulmonary
9%
Gastrointestinal/Nutrition
8%
Musculoskeletal
8%
Neurology
7%
Infectious Disease
7%
Psychiatry/Behavioral
7%
Reproductive
7%
Endocrine
6%
Eyes/Ears/Nose/Throat
6%
Hematology
5%
Renal
5%
Genitourinary
4%
Dermatology
4%

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For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

Home PharmacologyNitrofurantoin

Nitrofurantoin

Urinary Antiseptic

Drug Class: Urinary Antiseptic
Mechanism of Action (MOA): Reduced to reactive intermediates that damage bacterial DNA, ribosomes, and metabolic enzymes.
Clinical Notes: First-line for uncomplicated cystitis. Concentrates in urine only — not for pyelonephritis; avoid if CrCl <30. Pulmonary fibrosis with chronic use.
Source: FDA label

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