Ciprofloxacin

Fluoroquinolone
Drug Class
Fluoroquinolone
Mechanism of Action (MOA)
Inhibits DNA gyrase & topoisomerase IV → blocks DNA replication (bactericidal).
Black Box Warning
Tendinitis & tendon rupture, peripheral neuropathy, CNS effects; may worsen myasthenia gravis; reserve if no alternative.
Clinical Notes
Strong gram-negative (incl. Pseudomonas) coverage; chelated by cations; not first-choice in children; generally avoided in pregnancy.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

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Used for

Same family

Other antibiotics · 10 drugs

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