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For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

HomePharmacologyCiprofloxacin

Ciprofloxacin

Fluoroquinolone
Drug Class
Fluoroquinolone
Mechanism of Action (MOA)
Inhibits DNA gyrase & topoisomerase IV → blocks DNA replication (bactericidal).
Black Box Warning
Tendinitis & tendon rupture, peripheral neuropathy, CNS effects; may worsen myasthenia gravis.
Clinical Notes
Strong gram-negative (incl. Pseudomonas) coverage; chelated by cations; avoid in children/pregnancy when possible.
Source
FDA label (DailyMed)
All pharmacology