Lisinopril

ACE Inhibitor
Drug Class
ACE Inhibitor
Mechanism of Action (MOA)
Inhibits ACE → ↓ angiotensin II → vasodilation, ↓ aldosterone, ↓ afterload/preload.
Black Box Warning
Fetal toxicity — discontinue as soon as pregnancy is detected.
Clinical Notes
Dry cough (bradykinin) & angioedema are class effects. Watch K⁺ and creatinine.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

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Used for

Same family

ACE inhibitors & ARBs · 2 drugs

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