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For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

HomePharmacologyLisinopril

Lisinopril

ACE Inhibitor
Drug Class
ACE Inhibitor
Mechanism of Action (MOA)
Inhibits ACE → ↓ angiotensin II → vasodilation, ↓ aldosterone, ↓ afterload/preload.
Black Box Warning
Fetal toxicity — discontinue as soon as pregnancy is detected.
Clinical Notes
Dry cough (bradykinin) & angioedema are class effects. Watch K⁺ and creatinine.
Source
FDA label (DailyMed)
All pharmacology