Diltiazem

Calcium Channel Blocker (Non-Dihydropyridine)

Drug Class: Calcium Channel Blocker (Non-Dihydropyridine)
Mechanism of Action (MOA): Blocks L-type Ca²⁺ channels in myocardium & AV node → ↓ heart rate, ↓ AV conduction, ↓ contractility.
Clinical Notes: Rate control in AFib/SVT. Avoid combining with β-blockers (additive bradycardia/AV block) and in HFrEF (negative inotrope).
Source: FDA label (DailyMed)