Empagliflozin

SGLT2 Inhibitor
Drug Class
SGLT2 Inhibitor
Mechanism of Action (MOA)
Blocks SGLT2 in the proximal tubule → glucosuria (insulin-independent).
Clinical Notes
T2DM with cardiovascular/renal/HF benefit (now used in HFrEF and CKD even without diabetes). Genital mycotic infections, euglycemic DKA, volume depletion.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

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Used for

Same family

Diabetes drugs & insulins · 7 drugs

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