Glipizide
Sulfonylurea- Drug Class
- Sulfonylurea
- Mechanism of Action (MOA)
- Closes pancreatic β-cell K⁺-ATP channels → depolarization → insulin secretion.
- Clinical Notes
- Requires functioning β-cells. Hypoglycemia and weight gain are the main risks; glyburide is riskier in the elderly/renal disease.
- Source
- FDA label
Sources
Reviewed September 2026- FDA label — FDA / DailyMed
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