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PANCE Body Systems

Cardiovascular
11%
Pulmonary
9%
Gastrointestinal/Nutrition
8%
Musculoskeletal
8%
Neurology
7%
Infectious Disease
7%
Psychiatry/Behavioral
7%
Reproductive
7%
Endocrine
6%
Eyes/Ears/Nose/Throat
6%
Hematology
5%
Renal
5%
Genitourinary
4%
Dermatology
4%

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For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

Home PharmacologyFurosemide

Furosemide

Loop Diuretic

Drug Class: Loop Diuretic
Mechanism of Action (MOA): Inhibits Na⁺-K⁺-2Cl⁻ cotransporter in the thick ascending limb → potent natriuresis/diuresis.
Black Box Warning: Profound diuresis can cause fluid/electrolyte depletion — titrate to effect.
Clinical Notes: Watch for hypokalemia, ototoxicity (rapid IV), hyperuricemia.
Source: FDA label (DailyMed)

All pharmacology