Warfarin
Vitamin K Antagonist- Drug Class
- Vitamin K Antagonist
- Mechanism of Action (MOA)
- Inhibits VKORC1 → ↓ synthesis of vitamin-K-dependent factors II, VII, IX, X (and proteins C/S).
- Black Box Warning
- Major or fatal bleeding can occur.
- Clinical Notes
- Narrow therapeutic index; goal INR 2–3. Reverse with vitamin K / 4F-PCC.
- Source
- FDA label
Sources
Reviewed September 2026- FDA label — FDA / DailyMed
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Used for
Same family
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