Heparin (Unfractionated)

Anticoagulant (Unfractionated Heparin)
Drug Class
Anticoagulant (Unfractionated Heparin)
Mechanism of Action (MOA)
Activates antithrombin III → inactivates thrombin (IIa) and factor Xa.
Clinical Notes
Monitor aPTT; rapid on/off, reversible with protamine. Watch for HIT (heparin-induced thrombocytopenia). Preferred in pregnancy and renal failure.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

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Used for

Same family

Anticoagulants, antiplatelets & thrombolytics · 8 drugs

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