Enoxaparin
Low-Molecular-Weight Heparin- Drug Class
- Low-Molecular-Weight Heparin
- Mechanism of Action (MOA)
- Activates antithrombin III with preferential anti-Xa (over anti-IIa) activity.
- Black Box Warning
- Spinal/epidural hematoma with neuraxial anesthesia or spinal puncture — can cause long-term or permanent paralysis.
- Clinical Notes
- Predictable dosing, no routine monitoring (follow anti-Xa if needed). Lower HIT risk than UFH; renally cleared; only partial protamine reversal.
- Source
- FDA label
Sources
Reviewed September 2026- FDA label — FDA / DailyMed
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Used for
Same family
Anticoagulants, antiplatelets & thrombolytics · 8 drugs
- Heparin (Unfractionated) · Anticoagulant (Unfractionated Heparin)
- Aspirin · Antiplatelet (COX Inhibitor)
- Apixaban · Direct Factor Xa Inhibitor (DOAC)
- Clopidogrel · P2Y12 Inhibitor (Antiplatelet)
- Cilostazol · Phosphodiesterase-3 (PDE-3) Inhibitor
- Alteplase (tPA) · Thrombolytic
- Warfarin · Vitamin K Antagonist
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