Ezetimibe
Cholesterol Absorption Inhibitor- Drug Class
- Cholesterol Absorption Inhibitor
- Mechanism of Action (MOA)
- Blocks the intestinal NPC1L1 sterol transporter → ↓ absorption of dietary/biliary cholesterol → ↓ LDL.
- Clinical Notes
- Add-on to a statin when LDL goals aren't met (modest further LDL lowering; IMPROVE-IT showed added benefit). Generally well tolerated; rare myopathy/transaminitis when combined with a statin.
- Source
- FDA label
Sources
Reviewed September 2026- FDA label — FDA / DailyMed
Checked against the guideline or standard reference the exam keys to. If it has moved, use Report an error below.
Used for
Same family
Got a pharmacology lecture that covers Ezetimibe? Turn it into flashcards and board-style questions, free. Drop it on the home page
All pharmacology