Acute Kidney Injury

Renal · ~5% of blueprint

Pathophysiology: Abrupt ↓ GFR — prerenal (hypoperfusion), intrinsic (e.g., ATN), or postrenal (obstruction).
Signs & Symptoms: Often asymptomatic; ↓ urine output, edema, rising creatinine; uremia if severe.
Gold Standard Diagnosis: Rising creatinine / ↓ urine output (KDIGO); urine studies & FENa to localize the cause.
First-line Treatment: Treat the cause; optimize volume/perfusion, stop nephrotoxins; dialysis for refractory complications.

High-Yield Pearl

FENa <1% suggests prerenal; >2% suggests ATN. Dialysis indications: AEIOU.

More Renal conditions