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PANCE® is a registered trademark of the National Commission on Certification of Physician Assistants (NCCPA). This application is an independent study resource and is not affiliated with, sponsored by, or endorsed by the NCCPA.

For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

Flashcards

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Card 1 of 6
DiseaseDermatology

Atopic Dermatitis (Eczema)

Recall: Pathophysiology · S/Sx · Gold Standard Dx · First-line Tx · Pearl

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DiseaseDermatology

Atopic Dermatitis (Eczema)

Pathophysiology
Skin-barrier dysfunction + Th2 immune dysregulation → chronic relapsing inflammation; part of the atopic triad.
S/Sx
Pruritic, erythematous, scaly patches in flexural areas (antecubital/popliteal); chronic lichenification.
Gold Standard Dx
Clinical diagnosis — pruritus + typical morphology/distribution + a chronic relapsing course.
First-line Tx
Emollients + topical corticosteroids; topical calcineurin inhibitors; trigger avoidance.

Eczema is “the itch that rashes” — flexural distribution and part of the atopic triad.