Allopurinol
Xanthine Oxidase Inhibitor (Urate-Lowering)- Drug Class
- Xanthine Oxidase Inhibitor (Urate-Lowering)
- Mechanism of Action (MOA)
- Inhibits xanthine oxidase → ↓ uric acid production.
- Clinical Notes
- Chronic gout urate-lowering — not for acute flares (can trigger one; cover with colchicine/NSAID). Allopurinol hypersensitivity/SJS (HLA-B*58:01); reduce azathioprine dose if combined.
- Source
- FDA label
Sources
Reviewed September 2026- FDA label — FDA / DailyMed
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