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PANCE Body Systems

Cardiovascular
11%
Pulmonary
9%
Gastrointestinal/Nutrition
8%
Musculoskeletal
8%
Neurology
7%
Infectious Disease
7%
Psychiatry/Behavioral
7%
Reproductive
7%
Endocrine
6%
Eyes/Ears/Nose/Throat
6%
Hematology
5%
Renal
5%
Genitourinary
4%
Dermatology
4%

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For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

Home PharmacologyFamotidine

Famotidine

H2 Receptor Antagonist

Drug Class: H2 Receptor Antagonist
Mechanism of Action (MOA): Competitively blocks histamine H2 receptors on gastric parietal cells → ↓ acid secretion.
Clinical Notes: GERD/dyspepsia; faster onset but less potent than PPIs. Replaced ranitidine (NDMA recall). Confusion in the elderly/renal impairment.
Source: FDA label (DailyMed)

All pharmacology