- Drug Class
- Antidote (Glutathione Precursor)
- Mechanism of Action (MOA)
- Replenishes hepatic glutathione, detoxifying the reactive acetaminophen metabolite NAPQI; also a mucolytic.
- Clinical Notes
- Antidote for acetaminophen overdose — most effective within 8 h (dose by the Rumack-Matthew nomogram). Anaphylactoid reactions with IV use.
Sources
Reviewed September 2026- FDA label — FDA / DailyMed
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