Naloxone

Opioid Antagonist
Drug Class
Opioid Antagonist
Mechanism of Action (MOA)
Competitive µ-opioid receptor antagonist → reverses opioid effects.
Clinical Notes
Opioid overdose reversal (intranasal/IM/IV). Short half-life — may need repeat dosing; can precipitate acute withdrawal. Take-home kits save lives.
Source
FDA label

Sources

Reviewed June 2026
  1. FDA label — FDA / DailyMed

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Same family

Antidotes & reversal agents · 4 drugs

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