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HomePharmacologyMontelukast

Montelukast

Leukotriene Receptor Antagonist
Drug Class
Leukotriene Receptor Antagonist
Mechanism of Action (MOA)
Blocks the CysLT1 leukotriene receptor → ↓ bronchoconstriction and inflammation.
Black Box Warning
Serious neuropsychiatric events (agitation, depression, suicidal thinking and behavior).
Clinical Notes
Add-on for asthma, allergic rhinitis, and exercise-induced bronchospasm. Oral, once daily.
Source
FDA label (DailyMed)
All pharmacology