Salmeterol

Long-Acting β2 Agonist (LABA)
Drug Class
Long-Acting β2 Agonist (LABA)
Mechanism of Action (MOA)
Long-acting β2-adrenergic agonist → sustained bronchodilation.
Black Box Warning
Asthma-related death when used as monotherapy — in asthma, use only combined with an inhaled corticosteroid.
Clinical Notes
Always pair with an ICS in asthma; LABA monotherapy is acceptable in COPD. Not a rescue inhaler.
Source
FDA label

Sources

Reviewed September 2026
  1. FDA label — FDA / DailyMed

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Used for

Same family

Asthma & COPD drugs · 5 drugs

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