- Drug Class
- Triptan (5-HT1B/1D Agonist)
- Mechanism of Action (MOA)
- Serotonin 5-HT1B/1D agonist → cranial vasoconstriction and ↓ release of vasoactive peptides.
- Clinical Notes
- Acute migraine abortive. Contraindicated in CAD/uncontrolled HTN (coronary vasospasm); serotonin syndrome risk; do not combine with ergots.
Sources
Reviewed September 2026- FDA label — FDA / DailyMed
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