Atopic Dermatitis (Eczema)

Dermatology · ~4% of blueprint

Pathophysiology: Skin-barrier dysfunction + Th2 immune dysregulation → chronic relapsing inflammation; part of the atopic triad.
Signs & Symptoms: Pruritic, erythematous, scaly patches in flexural areas (antecubital/popliteal); chronic lichenification.
Gold Standard Diagnosis: Clinical diagnosis — pruritus + typical morphology/distribution + a chronic relapsing course.
First-line Treatment: Emollients + topical corticosteroids; topical calcineurin inhibitors; trigger avoidance.

High-Yield Pearl

Eczema is “the itch that rashes” — flexural distribution and part of the atopic triad.

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