Atopic Dermatitis (Eczema)
Dermatology · ~4% of blueprint- Pathophysiology
- Skin-barrier dysfunction + Th2 immune dysregulation → chronic relapsing inflammation; part of the atopic triad.
- Signs & Symptoms
- Pruritic, erythematous, scaly patches in flexural areas (antecubital/popliteal); chronic lichenification.
- Gold Standard Diagnosis
- Clinical diagnosis — pruritus + typical morphology/distribution + a chronic relapsing course.
- First-line Treatment
- Emollients + topical corticosteroids; topical calcineurin, PDE-4 or JAK inhibitors; trigger avoidance.
Drug cardsTriamcinolone (Topical Corticosteroid)
High-Yield Pearl
Eczema is “the itch that rashes” — flexural distribution and part of the atopic triad.
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Immunology & Genetics
Sources
Reviewed September 2026- Guidelines of Care for the Management of Atopic Dermatitis, Section 1: Diagnosis and assessment (2014) — American Academy of Dermatology, 2014
- Atopic dermatitis clinical guideline (recommendation summaries incl. 2023 topical instalment and 2025 focused update) — American Academy of Dermatology, 2026
- StatPearls: Atopic Dermatitis — StatPearls Publishing, 2026
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