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PANCE® is a registered trademark of the National Commission on Certification of Physician Assistants (NCCPA). This application is an independent study resource and is not affiliated with, sponsored by, or endorsed by the NCCPA.

For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

HomeDermatologyAtopic Dermatitis (Eczema)
🖐️

Atopic Dermatitis (Eczema)

Dermatology · ~4% of blueprint
🔬Pathophysiology
Skin-barrier dysfunction + Th2 immune dysregulation → chronic relapsing inflammation; part of the atopic triad.
🩺Signs & Symptoms
Pruritic, erythematous, scaly patches in flexural areas (antecubital/popliteal); chronic lichenification.
🎯Gold Standard Diagnosis
Clinical diagnosis — pruritus + typical morphology/distribution + a chronic relapsing course.
💊First-line Treatment
Emollients + topical corticosteroids; topical calcineurin, PDE-4 or JAK inhibitors; trigger avoidance.
Drug cardsTriamcinolone (Topical Corticosteroid)
High-Yield Pearl

Eczema is “the itch that rashes” — flexural distribution and part of the atopic triad.

Sources

Reviewed September 2026
  1. Guidelines of Care for the Management of Atopic Dermatitis, Section 1: Diagnosis and assessment (2014) — American Academy of Dermatology, 2014
  2. Atopic dermatitis clinical guideline (recommendation summaries incl. 2023 topical instalment and 2025 focused update) — American Academy of Dermatology, 2026
  3. StatPearls: Atopic Dermatitis — StatPearls Publishing, 2026

Checked against the guideline or standard reference the exam keys to. If it has moved, use Report an error below.

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