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PANCE® is a registered trademark of the National Commission on Certification of Physician Assistants (NCCPA). This application is an independent study resource and is not affiliated with, sponsored by, or endorsed by the NCCPA.

For educational use only. Content is AI-generated, may contain errors, and is not medical advice — always verify against current primary sources and faculty guidance before clinical use.

HomeDermatologyPsoriasis
🖐️

Psoriasis

Dermatology · ~4% of blueprint
🔬Pathophysiology
Immune-mediated (T-cell) keratinocyte hyperproliferation → thick scaly plaques.
🩺Signs & Symptoms
Well-demarcated erythematous plaques with silvery scale on extensor surfaces/scalp; nail pitting.
🎯Gold Standard Diagnosis
Clinical; biopsy if unclear (Munro microabscesses).
💊First-line Treatment
Topical corticosteroids + vitamin D analogs; phototherapy; biologics for severe disease.
Drug cardsTriamcinolone (Topical Corticosteroid)
High-Yield Pearl

Extensor plaques with silvery scale + nail pitting = psoriasis; Auspitz sign = pinpoint bleeding on scale removal.

Sources

Reviewed September 2026
  1. Psoriasis clinical guideline (AAD-NPF 2019-2021 series highlights) — American Academy of Dermatology / National Psoriasis Foundation, 2026
  2. Management of Adult Psoriasis with Topicals — AAD Guideline Clinical Pathway (May 2023 update) — American Academy of Dermatology, 2023
  3. StatPearls: Psoriasis — StatPearls Publishing, 2026

Checked against the guideline or standard reference the exam keys to. If it has moved, use Report an error below.

More Dermatology conditions

  • Atopic Dermatitis (Eczema)
  • Melanoma
All Dermatology