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HomePharmacologyGabapentin

Gabapentin

Anticonvulsant / Neuropathic Analgesic
Drug Class
Anticonvulsant / Neuropathic Analgesic
Mechanism of Action (MOA)
Binds the α2δ subunit of voltage-gated Ca²⁺ channels → ↓ excitatory neurotransmitter release.
Clinical Notes
Neuropathic pain, postherpetic neuralgia, adjunct seizures, restless legs. Sedation/dizziness; renally cleared; misuse potential.
Source
FDA label (DailyMed)
All pharmacology