Valproic Acid
Antiepileptic / Mood Stabilizer- Drug Class
- Antiepileptic / Mood Stabilizer
- Mechanism of Action (MOA)
- ↑ GABA and blocks Na⁺ channels → broad anticonvulsant effect.
- Black Box Warning
- Hepatotoxicity, life-threatening pancreatitis, and teratogenicity (neural tube defects).
- Clinical Notes
- Generalized epilepsy, bipolar, migraine prophylaxis. Avoid in pregnancy/childbearing potential. Weight gain, tremor, hyperammonemia, thrombocytopenia.
- Source
- FDA label
Sources
Reviewed September 2026- FDA label — FDA / DailyMed
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Used for
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