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HomePharmacologyVenlafaxine

Venlafaxine

Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Drug Class
Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Mechanism of Action (MOA)
Inhibits serotonin and (at higher doses) norepinephrine reuptake.
Black Box Warning
Increased suicidality in patients <25.
Clinical Notes
Depression, GAD, neuropathic pain. Dose-dependent ↑ blood pressure; pronounced discontinuation syndrome — taper carefully.
Source
FDA label (DailyMed)
All pharmacology